Scientific publications

2026

  • AI-Driven multi-view learning from CCTA for myocardial infarction diagnosis, Jakub Gwizdala, Adil Salihu, Ortal Senouf, David Meier, David Rotzinger, Salah Qanadli, Olivier Muller, Pascal Frossard, Emmanuel Abbe, Dorina Thanou, Stephane Fournier, and Denise Auberson, The International Journal of Cardiovascular Imaging doi:10.1007/s10554-025-03523-6
  • Elevated ANGPTL4 in stable post-ACS patients linked to long-term myocardial infarction risk: insights from the SPUM-ACS study, Kapka Miteva, Cedric Follonier, Louise Artels, David Carballo, David Nanchen, Baris Gencer, Thomas Lüscher, and François Mach, Atherosclerosis doi:10.1016/j.atherosclerosis.2026.121823
  • Future cardiovascular events prediction from invasive coronary angiography: A graph representation learning perspective, Xiaowu Sun, Theofilos Belmpas, Ortal Senouf; Emmanuel Abbé, Pascal Frossard, Bernard De Bruyne, Denise Auberson, Olivier Muller, Stephane Fournier, Thabo Mahendiran, and Dorina Thanou, Medical Image Analysis doi:10.1016/j.media.2026.104079
  • How will artificial intelligence improve cardiovascular prevention?, Alexandru A Mircea, Emmanuel Abbé, Adèle LC Mackowiak, Baris Gencer, Didier Locca, Murielle Bochud, and David Nanchen, Revue Médicale Suisse doi:10.53738/revmed.2026.22.952.48372
  • ODySSeI: An Open-Source End-to-End Framework for Automated Detection, Segmentation, and Severity Estimation of Lesions in Invasive Coronary Angiography Images, Anand Choudhary, Xiaowu Sun, Thabo Mahendiran, Ortal Senouf, Denise Auberson, Bernard De Bruyne, Stephane Fournier, Olivier Muller, Emmanuel Abbé, Pascal Frossard, and Dorina Thanou Link
  • One-Year Systolic Blood Pressure and Subsequent Cardiovascular Outcomes After Acute Coronary Syndrome: Insights from a Swiss Prospective Cohort, Henri Lu, Cédric Follonier, Louise Artels, David Carballo, David Nanchen, Thomas F Lüscher, Christian M Matter, Lorenz Raeber, Olivier Muller, Nicolas Rodondi, Grégoire Wuerzner, François Mach, and Baris Gencer, European Journal of Preventive Cardiology doi:10.1093/eurjpc/zwag531
  • Quantitative CCTA Plaque Differences Between Japanese and Non-Japanese Patients: Insights From ADVANCE, Alexander Haenel, Fionn Coughlan, John K. Khoo, Nicholas Ng, Hitoshi Matsuo, Hiromasa Otake, Campbell Rogers, Bjarne Linde Nørgaard, Jonathon Leipsic, and Georgios Tzimas, JACC: Advances doi:10.1016/j.jacadv.2026.103234
  • Reproducibility of AI-Informed Coronary Computed Tomography Angiography-Derived Coronary Plaque Volume Quantification, Dae-Won Kim, Biyanka Jaltotage, Tim Fonte, Nicholas Ng, Jonathon Leipsic, Georgios Tzimas, and Bethlehem Mengesha, JACC: Advances doi:10.1016/j.jacadv.2026.103001
  • Sex differences in detection of acute coronary syndrome culprit lesion using conventional and AI-enhanced coronary CT angiography, Hyun Jin Ahn, Seokhun Yang, Jae Wook Jung, Sang-Hyeon Park, Jinlong Zhang, Keehwan Lee, Doyeon Hwang, Kyu-Sun Lee, Sang-Hoon Na, Joon-Hyung Doh, Chang-Wook Nam, Tae Hyun Kim, Eun-Seok Shin, Eun Ju Chun, Su-Yeon Choi, Hyun Kuk Kim, Young Joon Hong, Hun-Jun Park, Song-Yi Kim, Mirza Husic, Jess Lambrechtsen, Jesper M Jensen, Bjarne L Nørgaard, Daniele Andreini, Pal Maurovich-Horvat, Bela Merkely, Martin Penicka, Bernard de Bruyne, Abdul Ihdayhid, Brian Ko, Georgios Tzimas, Jonathon Leipsic, Javier Sanz, Mark G Rabbat, Farhan Katchi, Moneal Shah, Nobuhiro Tanaka, Ryo Nakazato, Taku Asano, Mitsuyasu Terashima, Hiroaki Takashima, Tetsuya Amano, Yoshihiro Sobue, Hitoshi Matsuo, Hiromasa Otake, Takashi Kubo, Masahiro Takahata, Takashi Akasaka, Teruhito Kido, Teruhito Mochizuki, Hiroyoshi Yokoi, Taichi Okonogi, Tomohiro Kawasaki, Koichi Nakao, Tomohiro Sakamoto, Taishi Yonetsu, Tsunekazu Kakuta, Yohei Yamauchi, Charles A Taylor, Jeroen J Bax, Peter H Stone, Jagat Narula, Leslee J Shaw, and Bon-Kwon Koo, European Heart Journal - Cardiovascular Imaging doi:10.1093/ehjci/jeag270
  • The association of risk factors on coronary computed tomography angiography derived atherosclerotic plaque volume – Lessons from the ADVANCE registry, Alexander Haenel, Ruurt A. Jukema, John K. Khoo, Fionn Coughlan, Philipp Blanke, Aaisha Ferkh, Timothy Fairbairn, Nicholas Ng, Lynne M. Koweek, Pamela Douglas, Mark Rabbat, Gianluca Pontone, Kavitha M. Chinnaiyan, Bernard De Bruyne, Jeroen Bax, Tetsuya Amano, Koen Nieman, Campbell Rogers, Hironori Kitabata, Niels PR. Sand, Tomohiro Kawasaki, Sarah Mullen, Whitney Huey, Hitoshi Matsuo, Manesh Patel, Bjarne L. Nørgaard, Jonathon A. Leipsic, and Georgios Tzimas, Atherosclerosis doi:10.1016/j.atherosclerosis.2025.120515
  • Use of Mediterranean diet adherence and physical activity for refining cardiovascular risk prediction in the general population – insights from the CoLaus/PsyCoLaus study, Louise Artels, Pedro Marques-Vidal, Julien Vaucher, Peter Vollenweider, Roxane de la Harpe, Olivier Muller, Orestis Efthimiou, and Baris Gencer, European Journal of Preventive Cardiology doi:10.1093/eurjpc/zwag466
  • Weight change and long-term cardiovascular outcomes in overweight and obese patients after acute coronary syndromes, Louise Artels, Cédric Follonier, Stéphanie Baggio, David Carballo, David Nanchen, Kostantinos Koskinas, Christian M Matter, Lorenz Räber, Olivier Muller, Nicolas Rodondi, François Mach, Baris Gencer, European Heart Journal - Open doi:10.1093/ehjopen/oeag105
  • Which role for coronary CT angiography in cardiovascular prevention?, Adèle LC Mackowiak, Georgios Tzimas, Olivier Müller, and Baris Gencer, Revue Médicale Suisse doi:10.53738/revmed.2026.22.952.48472

2025

  • Artificial Intelligence-based Coronary Plaque Quantification Using Coronary CT Angiography: Current Insights and Future Directions, Ruurt A. Jukema, Philipp Blanke, John K. Khoo, Georgios Tzimas, Amir Ahmadi, Ibrahim Danad, Paul Knaapen, Stephanie L. Sellers, and Jonathon A. Leipsic, Radiology: Cardiothoracic Imaging doi:10.1148/ryct.240568
  • CM-UNet: a self-supervised learning-based model for coronary artery segmentation in X-ray angiography, Camille Challier, Xiaowu Sun, Thabo Mahendiran, Ortal Senouf, Bernard De Bruyne, Denise Auberson, Olivier Müller, Stephane Fournier, Pascal Frossard, Emmanuel Abbé, and Dorina Thanou, IEEE EMBC doi:10.1109/EMBC58623.2025.11253755
  • Physics-informed self-supervised learning for predictive modeling of coronary artery digital twins, Xiaowu Sun, Thabo Mahendiran, Ortal Senouf, Denise Auberson, Bernard De Bruyne, Stephane Fournier, Olivier Muller, Pascal Frossard, Emmanuel Abbe, Dorina Thanou Link
  • Relation of Coronary Artery Disease and High-Sensitivity Cardiac Troponin: Evaluation with CCTA and AI-enabled Plaque Quantification, Oliver Haidari Mattea Lewis, Elina Khasanova, Anthony Chuang, David Meier, Stéphane Fournier, Philipp Blanke, Frank Scheuermeyer, Jonathon Leipsic, Damini Dey, Stephanie Sellers, and Georgios Tzimas, Radiology: Cardiothoracic Imaging doi:10.1148/ryct.250002
  • The Association Between Cardiac Symptoms and Coronary Plaque: An ADVANCE Substudy, Ruurt A. Jukema, Philipp Blanke, John K. Khoo, Georgios Tzimas, Aaisha Ferkh, Timothy Fairbairn, Koen Nieman, Manesh Patel, Bjarne L. Nørgaard, and Jonathon A. Leipsic, JACC: Cardiovascular Imaging doi:10.1016/j.jcmg.2025.05.002
  • AngioPy Segmentation: An open-source, user-guided deep learning tool for coronary artery segmentation., Mahendiran, Thabo, Dorina Thanou, Ortal Senouf, Yassine Jamaa, Stephane Fournier, Bernard De Bruyne, Emmanuel Abbé, Olivier Muller, and Edward Andò., International journal of cardiology doi:10.1016/j.ijcard.2024.132598

2024

  • Anatomy-informed multimodal learning for myocardial infarction prediction, Ivan-Daniel Sievering, Ortal Senouf, Thabo Mahendiran, David Nanchen, Stephane Fournier, Olivier Muller, Pascal Frossard, Emmanuel Abbé, and Dorina Thanou, IEEE Open Journal of Engineering in Medicine and Biology doi:10.1109/OJEMB.2024.3403948
  • Diagnostic Performance of AI-enabled Plaque Quantification from Coronary CT Angiography Compared with Intravascular Ultrasound, Abdul Rahman Ihdayhid, Georgios Tzimas, Kersten Peterson, Nicholas Ng, Saba Mirza, Akiko Maehara, and Robert D. Safian, Radiology: Cardiothoracic Imaging doi:10.1148/ryct.230312
  • Interaction of AI-Enabled Quantitative Coronary Plaque Volumes on Coronary CT Angiography, FFRCT, and Clinical Outcomes: A Retrospective Analysis of the ADVANCE Registry, James Dundas, Jonathon Leipsic, Timothy Fairbairn, Nicholas Ng, Vida Sussman, Ilana Guez, Rachael Rosenblatt, Lynne M. Hurwitz Koweek, Pamela S. Douglas, Mark Rabbat, Gianluca Pontone, Kavitha Chinnaiyan, Bernard de Bruyne, Jeroen J. Bax, Tetsuya Amano,, Koen Nieman, Campbell Rogers, Hironori Kitabata, Niels P.R. Sand, Tomohiro Kawasaki, Sarah Mullen, Whitney Huey, Hitoshi Matsuo, Manesh R. Patel, Bjarne L. Norgaard, Amir Ahmadi, and Georgios Tzimas, Circulation: Cardiovascular Imaging doi:10.1161/CIRCIMAGING.123.016143
  • A study of ChatGPT in facilitating Heart Team decisions on severe aortic stenosis, Adil Salihu, David Meier, Nathalie Noirclerc, Ioannis Skalidis, Sarah Mauler-Wittwer, Frédérique Recordon, Matthias Kirsch, Christan Roguelov, Alexandre Berger, Xiaowu Sun, Emmanuel Abbe, Carlo Marcucci, Valentina Rancati, Lorenzo Rosner, Emmanuelle Scala, David C. Rotzinger, Marc Humbert, Olivier Muller, Henri Lu, and Stephane Fournier, EuroIntervention doi:10.4244/EIJ-D-23-00643
  • Graph Neural Network based Future Clinical Events Prediction from Invasive Coronary Angiography, Xiaowu Sun, Theofilos Belmpas, Ortal Senouf, Emmanuel Abbé, Pascal Frossard, Bernard De Bruyne, Olivier Muller, Stéphane Fournier, Thabo Mahendiran, and Dorina Thanou, IEEE ISBI doi:10.1109/ISBI56570.2024.10635813

2023

  • Age- and Sex-Specific Nomographic CT Quantitative Plaque Data From a Large International Cohort, Georgios Tzimas, Gaurav S. Gulsin, Russell J. Everett, Mariama Akodad, David Meier, Kavishka Sewnarain, Zain Ally, Rawan Alnamasy, Nicholas Ng, Sarah Mullen, David Rotzinger, Janarthanan Sathananthan, Stephanie L. Sellers, Philipp Blanke, and Jonathon A. Leipsic, JACC: Cardiovascular Imaging doi:10.1016/j.jcmg.2023.05.011
  • Can knowledge transfer techniques compensate for the limited myocardial infarction data by leveraging haemodynamics? An in silico study, Riccardo Tenderini, Federico Betti, Ortal Yona Senouf, Olivier Muller, Simone Deparis, Annalisa Buffa, and Emmanuel Abbé, International Conference on Artificial Intelligence in Medicine doi:10.1007/978-3-031-34344-5_26
  • Can smart devices and AI in cardiology improve clinical practice?, Niccolo Maurizi, Ioannis Skalidis, Denise Auberson, Thabo Mahendiran, Stephane Fournier, Emmanuel Abbe, and Olivier Muller, Revue medicale suisse doi:10.53738/REVMED.2023.19.828.1041
  • ChatGPT takes on the European Exam in Core Cardiology: an artificial intelligence success story?, Ioannis Skalidis, Aurélien Cagnina, Wongsakorn Luangphiphat, Thabo Mahendiran, Olivier Müller, Emmanuel Abbé, and Stéphane Fournier, European Heart Journal - Digital Health doi:10.1093/ehjdh/ztad029
  • Deep learning-based prediction of future myocardial infarction using invasive coronary angiography: a feasibility study, Thabo Mahendiran, Dorina Thanou, Ortal Senouf, David Meier, Nicolas Dayer, Fahrang Aminfar, Denise Auberson, Omar Raita, Pascal Frossard, Mattia Pagnoni, Stéphane Cook, Bernard De Bruyne, Olivier Muller, Emmanuel Abbé, and Stephane Fournier, Open Heart doi:10.1136/openhrt-2022-002237
  • Towards AI-assisted cardiology: a reflection on the performance and limitations of using large language models in clinical decision-making, Adil Salihu, Mehdi Ali Gadiri, Ioannis Skalidis, David Meier, Denise Auberson, Annick Fournier, Romain Fournier, Dorina Thanou, Emmanuel Abbé, Olivier Muller, and Stephane Fournier, EuroIntervention doi:10.4244/EIJ-D-23-00461

2022

  • Artificial Intelligence and Cardiology: The Machine is Launched, Olivier Muller, Emmanuel Abbé, and François Mach, Revue Médicale Suisse doi:10.53738/REVMED.2022.18.783.1027
  • Attention-based learning of views fusion applied to myocardial infarction diagnosis from x-ray CT, Jakub Gwizdala, Ortal Senouf, Denise Auberson, David Meier, David Rotzinger, Stephane Fournier, Salah Qanadli, Olivier Muller, Pascal Frossard, Emmanuel Abbé, and Dorina Thanou, Medical Imaging meets NeurIPS Link

2021

  • Predicting future myocardial infarction from angiographies with deep learning, Dorina Thanou, Ortal Senouf, Omar Raita, Emmanuel Abbé, Pascal Frossard, Farhang Aminfar, Denise Auberson, Nicolas Dayer, David Meier, Mattia Pagnoni, Olivier Muller, Stéphane Fournier, and Thabo Mahendiran, Medical Imaging meets NeurIPS Link